Here we developed the first database concerning Sex Differences in Cancer (SDC), a web-based public database that integrates resources from multiple databases. SDC contains 27 types of cancers, 6 types of molecular data, more than 10,000 donors and 977 cancer cell lines were used for the analysis of sex differences among cancers. It provides five main modules: survival and phenotype, molecular differences, signatures and pathways, therapy response, download. Users can download the visualized results and raw data after analysis. Collectively, the SDC is the first integrated database to describe sex differences in cancer on the web server, which will strengthen our understanding of the role of sex in cancers. The SDC is implemented in Shiny-server and freely available for public use at http://sdc.yichaozheng.cn or http://sdc.anticancer.xyz.
Cite us!
L.-F. Zhao, J.-G. Zhang, F.-Y. Qi, W.-Y. Hou, Y.-R. Li, D.-D. Shen, L.-J. Zhao, L. Qi, H.-M. Liu, Y.-C. Zheng, SDC: An Integrated Database for Sex Differences in Cancer, Computational and Structural Biotechnology Journal (2022). https://doi.org/10.1016/j.csbj.2022.02.023 .